Progression of alcoholic liver disease moves through several distinct phase from development of fatty liver to the development of alcoholic hepatitis and cirrhosis

Progression of alcoholic liver disease moves through several distinct phase from development of fatty liver to the development of alcoholic hepatitis and cirrhosis. Fatty liver and alcoholic hepatitis may be reversible with cessation of alcohol intake, but cirrhosis itself is irreversible. .
Passive immunity can be of globulin containing antibody to the virus (normal immunoglobulin; prepared from pooled plasma from known immune donors) which confers temporary protection for travellers visiting areas where the virus is endemic. Active immunization with hepatitis a vaccine is now preferable
Chronic carriage occur ion about 5% of those infected but is more common in the immune compromised and in other high risk group including male homosexual and intravenous drug abusers